Table 3. Univariate and multivariate analysis of prognostic factors of overall survival in the training cohort.

Variable	Univariate analysis			Multivariate analysis
	Hazard ratio (95% CI)	P		Hazard ratio (95% CI)	P
Age (<70/≥70)	0.64 (0.25-2.2)	0.43		0.48 (0.17-1.69)	0.22
Sex (female/male)	0.18 (0.029-0.58)	0.0019		0.20 (0.032-0.66)	0.0053
Histologic subtype (epithelioid/others)	0.44 (0.21-0.99)	0.048		0.75 (0.35-1.77)	0.49
Pathological stage (I-II/III-IV)	0.26 (0.042-0.86)	0.025		0.51 (0.24-1.15)	0.10
Treatment (trimodality/no trimodality)	0.86 (0.46-1.7)	0.65
Hemoglobin (g/L) (<15.6/≥15.6)	1.81 (0.71-6.1)	0.23
WBC count (×109/L) (<5.7/≥5.7)	0.23 (0.055-0.64)	0.0028
Neutrophil count (×109/L) (<3.9/≥3.9)	0.40 (0.16-0.86)	0.018
Lymphocyte count (×109/L) (<1.0/≥1.0)	2.26 (0.94-4.9)	0.068
Platelet count (×109/L) (<350/≥350)	0.38 (0.20-0.74)	0.005
NLR (<3.5/≥3.5)	0.51 (0.27-0.97)	0.041
PLR (<215/≥215)	0.49 (0.26-0.93)	0.030		0.50 (0.24-0.99)	0.049

WBC, white blood cell; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.