Fig 2.

A, Relationship between DTI scores and NMF levels at first presentation of disease (squares) and after 6 weeks of topical therapy with skin care regimens and appropriate topical steroids (circles), with corresponding correlation coefficients (r). B, Linear regression analysis of log-transformed DTI scores and NMF levels at first presentation of disease (squares) and after 6 weeks of topical therapy with skin care regimens and appropriate topical steroids (circles). □ ○, Patients with AD wild-type with respect to FLG LOF mutations; ◓, ◨, patients with AD heterozygous for FLG LOF mutations; ⊗⊠, patients with AD homozygous or compound heterozygous for FLG LOF mutations.