Table 1. CD117, PDGFRA, and DOG1 expression rates and clinical pathological parameters analysis in GIST patients.
| Clinical features | n | CD117 |
PDGFRA |
DOG1 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| − | +~+++ | χ2/P | − | +~+++ | χ2/P | − | +~+++ | χ2/P | ||||
| Gender | 0.000/1.000 | 0.276/0.599 | 0.009/0.924 | |||||||||
| Men | 51 | 3 | 48 | 25 | 26 | 4 | 47 | |||||
| Women | 48 | 3 | 45 | 21 | 27 | 5 | 43 | |||||
| Age (years) | 0.000/1.000 | 0.648/0.421 | 0.000/1.000 | |||||||||
| ≤50 | 32 | 2 | 30 | 13 | 19 | 3 | 29 | |||||
| >50 | 67 | 4 | 63 | 33 | 34 | 6 | 61 | |||||
| Tumor size (cm) | 0.302/0.583 | 2.820/0.093 | 0.738/0.390 | |||||||||
| ≤5 | 47 | 4 | 43 | 26 | 21 | 6 | 41 | |||||
| >5 | 52 | 2 | 50 | 20 | 32 | 3 | 49 | |||||
| Tumor location | 4.458/0.108 | 5.006/0.082 | 1.328/0.515 | |||||||||
| Stomach | 50 | 1 | 49 | 20 | 30 | 3 | 47 | |||||
| Small intestine | 28 | 4 | 24 | 18 | 10 | 3 | 25 | |||||
| Colon and rectum | 21 | 1 | 20 | 8 | 13 | 3 | 18 | |||||
| Histological type | 3.334/0.189 | 0.404/0.817 | 0.806/0.668 | |||||||||
| Spindle cell type | 74 | 4 | 70 | 34 | 40 | 6 | 68 | |||||
| Epithelioid cell type | 13 | 0 | 13 | 7 | 6 | 1 | 12 | |||||
| Mixed type | 12 | 2 | 10 | 5 | 7 | 2 | 10 | |||||
| Degree of risk | 4.337/0.227 | 3.030/0.387 | 4.837/0.184 | |||||||||
| Extremely low | 12 | 1 | 11 | 3 | 9 | 1 | 11 | |||||
| Low | 29 | 1 | 28 | 13 | 16 | 3 | 26 | |||||
| Moderate | 37 | 4 | 33 | 19 | 18 | 5 | 32 | |||||
| High | 21 | 0 | 21 | 11 | 10 | 0 | 21 | |||||
GIST, gastrointestinal stromal tumor.