Table 2. The sensitivities and specificities of CD117 and PDGFRA, alone or in combination with DOG1, in the diagnosis GIST.
Parameters | Sensitivity | Specificity | Positive likelihood ratio | Negative likelihood ratio | Diagnostic odds ratio | Area under ROC curve |
---|---|---|---|---|---|---|
CD117 | 0.989 | 0.800 | 4.945 | 0.014 | 372.000 | 0.945 |
PDGFRA | 0.981 | 0.343 | 1.493 | 0.055 | 27.652 | 0.748 |
DOG1 | 0.968 | 0.710 | 3.338 | 0.045 | 73.333 | 0.895 |
CD117 + DOG1 | 0.960 | 0.840 | 6.000 | 0.048 | 61.071 | 0.895 |
PDFGRA + DOG1 | 0.933 | 0.947 | 17.604 | 0.071 | 252.000 | 0.840 |
CD117 + PDGFRA + DOG1 | 0.961 | 0.955 | 21.356 | 0.041 | 2,352.000 | 0.975 |
GIST, gastrointestinal stromal tumor.