Table 4. Univariate analysis for factors related to overall survival following reirradiation.

Factor analyzed	Negative predictive factor	P value
Karnofsky performance status	≤70	0.02
Gender	Female	0.49
Age	>45 years	0.46
Tumor location		0.78
Tumor size	>5 cm	0.42
Histopathological subtype	GBM	0.14
Extend of surgery	No surgery	0.95
Biological effective dose (BED) cumulative	<120 Gy	0.44
Whole brain dose	<25 Gy	0.42
Use of temozolomide	No	0.70

GBM, glioblastoma multiforme.