Table 2.

Multivariable adjusted odds ratios (ORs) for having an abnormal stress MPI study for clinical variables.

Variable	N	Normal/Abnormal Stress MPI	OR	95% CI	p-value
Cardiomyopathy	179	13/166	10.95	6.20–19.30	< 0.001
Prior MI	593	97/486	4.84	3.85–6.08	< 0.001
Male sex	2146	587/1559	4.72	4.13–5.39	< 0.001
CHF	873	191/682	3.67	3.08–4.37	< 0.001
Pharmacological stress	2433	819/1614	3.08	2.70–3.51	< 0.001
Inpatient	610	143/467	3.04	2.49–3.70	< 0.001
Known CAD	1288	364/924	2.75	2.39–3.18	< 0.001
Anti-arrhythmics	118	28/90	2.63	1.72–4.04	< 0.001
Prior CABG	391	115/276	2.05	1.63–2.57	< 0.001
Angina	869	274/595	2.00	1.71–2.35	< 0.001
ACE/ARB	2341	878/1463	1.96	1.73–2.23	< 0.001
Prior PCI	598	185/413	1.96	1.63–2.36	< 0.001
Arrhythmia	791	255/536	1.89	1.61–2.23	< 0.001
Valvular heart disease	143	46/97	1.72	1.20–2.45	0.003
Beta-blockers	2154	825/1329	1.71	1.51–1.94	< 0.001
Age > 65 years	2049	780/1269	1.70	1.50–1.93	< 0.001
Lipid lowering agent	2284	888/1396	1.68	1.48–1.91	< 0.001
Diabetes	1327	504/823	1.48	1.30–1.70	< 0.001
Nitrates	1879	775/1104	1.28	1.13–1.45	< 0.001
COPD	781	312/469	1.25	1.07–1.47	0.005
Hypertension	2453	1063/1390	1.12	0.99–1.27	0.08
Hyperlipidemia	977	443/534	0.95	0.82–1.10	0.50

Derived from the development data. MI=myocardial infarction, PCI=percutaneous coronary intervention, CABG=coronary artery bypass graft, ACE/ARB=angiotensin converting enzyme inhibitor/angiotensin receptor blocker, CHF=congestive heart failure, COPD=chronic obstructive pulmonary disease CAD coronary artery disease. p- values significant after Benjamini-Hochberg correction are indicated in bold.