Table 38

Malignant esophageal disease (clinical characteristics)

	Operation (+)					EMR or ESD	Operation (−)	Total
	Cases	30-day mortality			Hospital mortality
		Total	Hospital	After discharge
1. Esophageal cancer	5824	41 (0.7)	41 (0.7)	0	114 (2.0)	1853	2417	10,094
Location								0
(1) Cervical esophagus	195	0	0	0	3 (1.5)	80	178	453
(2) Thoracic esophagus	4758	32 (0.7)	32 (0.7)	0	98 (2.1)	1332	1847	7937
(3) Abdominal esophagus	605	6 (1.0)	6 (1.0)	0	9 (1.5)	70	66	741
(4) Multiple cancers	262	2 (0.8)	2 (0.8)	0	3 (1.1)	130	59	451
(5) Others/not described	4	1 (25.0)	1 (25.0)	0	1 (25.0)	241	267	512
Tumor depth
(A) Superficial cancer (T1)	1799	8 (0.4)	8 (0.4)	0	19 (1.1)	1757	192	3748
Mucosal cancer (T1a)	425	1 (0.2)	1 (0.2)	0	2 (0.5)	1285	24	1734
(B) Advanced cancer (T2–T4)	4025	33 (0.8)	33 (0.8)	0	94 (2.3)	1	2198	6224
(C) Not specified	0	0	0	0	0	95	27	122
2. Multiple primary cancers	984	6 (0.6)	6 (0.6)	0	19 (1.9)	355	323	1662
1) Synchronous	553	4 (0.7)	4 (0.7)	0	11 (2.0)	146	174	873
(1) Head and neck	166	0	0	0	0	67	50	283
(2) Stomach	197	1 (0.5)	1 (0.5)	0	2 (1.0)	43	65	305
(3) Others	157	3 (1.9)	3 (1.9)	0	8 (5.1)	23	49	229
(4) Triple cancers	24	0	0	0	0	13	6	43
(5) Unknown	9	0	0	0	1 (11.1)	0	4	13
2) Metachronous	428	2 (0.5)	2 (0.5)	0	8 (1.9)	209	149	786
(1) Head and neck	94	1 (1.1)	1 (1.1)	0	0	63	40	197
(2) Stomach	103	0	0	0	2 (1.9)	59	31	193
(3) Others	197	1 (0.5)	1 (0.5)	0	4 (2.0)	59	63	319
(4) Triple cancers	32	0	0	0	1 (3.1)	28	12	72
(5) Unknown	2	0	0	0	1 (50.0)	0	3	5
Unknown	3	0	0	0	0	0	0	0

Values in parenthesis represent mortality %

EMR endoscopic mucosal resection (including endoscopic submucosal dissection)