Table 6.
Postcompression evaluation of tablets containing solid dispersion.
| Formulation code | Weight variation (%) | Crushing strengtha (N) | Thicknessa (mm) | Friability (%) | Drug contentb (%) | Disintegration time (sec) |
|---|---|---|---|---|---|---|
| SD-01 | ±2.41 | 103.41 ± 0.97 | 3.42 ± 0.37 | 0.45 | 99.23 ± 0.09 | 398 ± 25 |
| SD-02 | ±2.77 | 82.33 ± 1.10 | 3.57 ± 0.20 | 0.31 | 101.06 ± 0.08 | 391 ± 41 |
| SD-03 | ±3.09 | 96.59 ± 0.38 | 3.51 ± 0.19 | 0.49 | 101.37 ± 0.31 | 386 ± 34 |
| SD-04 | ±2.58 | 89.22 ± 0.13 | 3.69 ± 0.21 | 0.62 | 100.79 ± 0.11 | 395 ± 46 |
| SD-05 | ±2.96 | 90.08 ± 0.62 | 3.65 ± 0.31 | 0.3 | 99.54 ± 0.41 | 391 ± 54 |
Results are presented as Mean ± S.D.
Data have been rounded off to two digits after decimal point.
a
n = 10.
b
n = 3.