Table 2. Demographic and Clinical characteristics of the study population.
Variable | Nomal (n = 60) | FLD (n = 60) | HSAP (n = 60) | NHSAP (n = 60) | P value |
---|---|---|---|---|---|
Sex(males),n | 30 | 30 | 30 | 30 | NS |
% | 50 | 50 | 50 | 50 | NS |
Age(years) | 43 ± 10 | 45 ± 11 | 44 ± 13 | 47 ± 15 | NS |
Range | (26–62) | (21–64) | (24–67) | (18–74) | NS |
BMI(kg/m2),mean | 21.1 | 31 | 29.9 | 23.6 | <0.05a |
Range | (18–24) | (28–36) | (27–34) | (19–25) | <0.05a |
AAT(mg/ml) | 2.54 ± 0.21 | 2.30 ± 0.27 | 1.63 ± 0.34 | 3.92 ± 0.37 | <0.01b |
Range | (2.16–2.90) | (1.81–2.69) | (0.74–2.59) | (3.1–4.78) | <0.01b |
Pathogenesis | |||||
Gallstones, n(%) | — | — | 22(37) | 25(42) | NS |
Alcohol, n(%) | — | — | 7(12) | 9(15) | NS |
Greasydiet, n(%) | — | — | 26(43) | 21(35) | NS |
ERCP, n(%) | — | — | 2(3) | 1(2) | NS |
Others, n(%) | — | — | 3(5) | 4(6) | NS |
Complications | |||||
SIRS, n(%) | — | — | 38(63) | 23(38) | <0.01c |
ARDS, n(%) | — | — | 28(47) | 11(18) | <0.01c |
MD, n(%) | — | — | 32(53) | 12(20) | <0.01c |
MODS, n(%) | — | — | 12(20) | 3(5) | <0.01 |
Fatty liver CT score (L/S) | |||||
Mean | 1.04 | 0.5 | 0.4 | 1.03 | <0.05d |
Range | (1.01–1.06) | (0.3–0.7) | (0.2–0.6) | (1.02–1.05) | <0.05d |
Fora and Ford: HSAP and FLD group vs. NHSAP and normal group, P < 0.05. Forb see Fig. 5a and forc see Fig. 4. ERCP, endoscopic retrograde cholangiopancreatography; SIRS, systemic inflammatory response syndrome; MD, metabolic disturbances; MODS, multiple organ dysfunction symdrome; BMI, body mass index; CT, computed tomography; NS, not significant.