TABLE 4.
Crude and Adjusted Incidence Rates for Rotavirus Gastroenteritis (GE), Lwak (January 1, 2007, to December 31, 2010)
| Syndrome | Rotavirus cases |
PYO | Crude IR |
95% CI
|
% GE | Adjusted
|
% GE Cases Visiting Field Clinic |
Adjusted
|
PAF | Final Adjusted
|
95% CI
|
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lower | Upper | Sampled at Clinic |
Cases 1 | Rate 1 | Cases 2 | Rate 2 | Cases 3 | Rate 3 | Lower | Upper | |||||||
| Age | |||||||||||||||||
| <12 months | Overall | 23 | 3426 | 671 | 446.1 | 1010.2 | 267 | 7803.6 | 498 | 14,549.5 | 0.93 | 462 | 13 494 | 12 318 | 14 782 | ||
| Dehydration | 16 | 3426 | 467 | 286.1 | 762.3 | 15.8 | 101 | 2955.2 | 60.2 | 168 | 4910.7 | 0.93 | 156 | 4 555 | 3 893 | 5 328 | |
| Dysentery | 0 | 3426 | 0 | 0.0 | 0.0 | 12.5 | 0 | 0.0 | 61.5 | 0 | 0.0 | 0.93 | 0 | 0 | 0 | 0 | |
| Mild diarrhea | 7 | 3426 | 204 | 97.4 | 428.6 | 4.2 | 166 | 4848.4 | 50.3 | 330 | 9638.7 | 0.93 | 306 | 8 940 | 7 992 | 9 999 | |
| 12–23 months | Overall | 20 | 3242 | 617 | 398.0 | 956.2 | 277 | 8547.2 | 524 | 16,158.0 | 0.93 | 486 | 14 986 | 13 711 | 16 380 | ||
| Dehydration | 14 | 3242 | 432 | 255.8 | 729.2 | 15.7 | 89 | 2745.8 | 60.8 | 146 | 4514.8 | 0.93 | 136 | 4 187 | 3 539 | 4 954 | |
| Dysentery | 0 | 3242 | 0 | 0.0 | 0.0 | 8.0 | 0 | 0.0 | 100 | 0 | 0.0 | 0.93 | 0 | 0 | 0 | 0 | |
| Mild diarrhea | 6 | 3242 | 185 | 83.1 | 412.0 | 3.2 | 188 | 5801.3 | 49.8 | 377 | 11,643.2 | 0.93 | 350 | 10 799 | 9 725 | 11 991 | |
| 24–59 months | Overall | 6 | 9275 | 65 | 29.1 | 144.0 | 94 | 1018.3 | 177 | 1907.9 | 0.93 | 164 | 1 770 | 1 519 | 2 062 | ||
| Dehydration | 2 | 9275 | 22 | 5.4 | 86.2 | 15.3 | 13 | 141.4 | 56.2 | 23 | 251.5 | 0.93 | 22 | 233 | 153 | 356 | |
| Dysentery | 0 | 9275 | 0 | 0.0 | 0.0 | 13.9 | 0 | 0.0 | 75.0 | 0 | 0.0 | 0.93 | 0 | 0 | 0 | 0 | |
| Mild diarrhea | 4 | 9275 | 43 | 16.2 | 114.9 | 4.9 | 81 | 876.9 | 52.9 | 154 | 1656.4 | 0.93 | 142 | 1 536 | 1 304 | 1 810 | |
| <5 years | Overall | 49 | 15,943 | 307 | 232.3 | 406.7 | 621 | 3893.0 | 1165 | 7308.7 | 0.93 | 1081 | 6 779 | 6 386 | 7 195 | ||
| Dehydration | 32 | 15,943 | 201 | 141.9 | 283.8 | 15.7 | 204 | 1281.2 | 59.3 | 345 | 2161.5 | 0.93 | 320 | 2 005 | 1 797 | 2 237 | |
| Dysentery | 0 | 15,943 | 0 | 0.0 | 0.0 | 11.9 | 0 | 0.0 | 68.2 | 0 | 0.0 | 0.93 | 0 | 0 | 0 | 0 | |
| Mild diarrhea | 17 | 15,943 | 107 | 66.3 | 171.5 | 4.1 | 416 | 2611.9 | 50.7 | 821 | 5147.1 | 0.93 | 761 | 4 774 | 4 446 | 5 125 | |
| 5–9 years | Overall | 3 | 19,443 | 15 | 5.0 | 47.8 | 42 | 215.1 | 90 | 460.4 | 0.89 | 79 | 408 | 328 | 509 | ||
| Dehydration | 0 | 19,443 | 0 | 0.0 | 0.0 | 12.9 | 0 | 0.0 | 54.1 | 0 | 0.0 | 0.89 | 0 | 0 | 0 | 0 | |
| Dysentery | 0 | 19,443 | 0 | 0.0 | 0.0 | 20.0 | 0 | 0.0 | 40.0 | 0 | 0.0 | 0.89 | 0 | 0 | 0 | 0 | |
| Mild diarrhea | 3 | 19,443 | 15 | 5.0 | 47.8 | 7.2 | 42 | 215.1 | 46.7 | 90 | 460.4 | 0.89 | 79 | 408 | 328 | 509 | |
| 10–17 years | Overall | 11 | 18,818 | 58 | 32.4 | 105.6 | 72 | 384.5 | 121 | 645.4 | 0.89 | 108 | 573 | 474 | 692 | ||
| Dehydration | 0 | 18,818 | 0 | 0.0 | 0.0 | 31.4 | 0 | 0.0 | 54.8 | 0 | 0.0 | 0.89 | 0 | 0 | 0 | 0 | |
| Dysentery | 6 | 18,818 | 32 | 14.3 | 71.0 | 23.0 | 26 | 138.6 | 80.0 | 33 | 173.3 | 0.89 | 29 | 154 | 107 | 221 | |
| Mild diarrhea | 5 | 18,818 | 27 | 11.1 | 63.8 | 10.8 | 46 | 245.9 | 52.1 | 89 | 472.1 | 0.89 | 79 | 419 | 336 | 522 | |
| 18–34 years | Overall | 32 | 23,725 | 135 | 95.4 | 190.7 | 148 | 624.8 | 272 | 1146.8 | 0.89 | 241 | 1 017 | 897 | 1 154 | ||
| Dehydration | 3 | 23,725 | 13 | 4.1 | 39.2 | 21.2 | 14 | 59.6 | 60.7 | 23 | 98.1 | 0.89 | 21 | 87 | 57 | 134 | |
| Dysentery | 9 | 23,725 | 38 | 19.7 | 72.9 | 40.5 | 22 | 93.6 | 73.7 | 30 | 127.0 | 0.89 | 27 | 113 | 77 | 165 | |
| Mild diarrhea | 20 | 23,725 | 84 | 54.4 | 130.7 | 17.9 | 112 | 471.7 | 51.2 | 219 | 921.7 | 0.89 | 194 | 818 | 710 | 941 | |
| 35–49 years | Overall | 11 | 10,312 | 107 | 59.1 | 192.6 | 42 | 411.8 | 76 | 736.3 | 0.89 | 67 | 653 | 515 | 830 | ||
| Dehydration | 0 | 10,312 | 0 | 0.0 | 0.0 | 19.5 | 0 | 0.0 | 57.0 | 0 | 0.0 | 0.89 | 0 | 0 | 0 | 0 | |
| Dysentery | 6 | 10,312 | 58 | 26.1 | 129.5 | 35.6 | 17 | 163.6 | 61.9 | 27 | 264.2 | 0.89 | 24 | 234 | 157 | 349 | |
| Mild diarrhea | 5 | 10,312 | 48 | 20.2 | 116.5 | 19.5 | 26 | 248.2 | 52.6 | 49 | 472.1 | 0.89 | 43 | 419 | 311 | 564 | |
| 50+ years | Overall | 10 | 13,977 | 72 | 38.5 | 133.0 | 52 | 374.1 | 99 | 705.8 | 0.89 | 88 | 626 | 508 | 772 | ||
| Dehydration | 4 | 13,977 | 29 | 10.7 | 76.3 | 18.6 | 21 | 153.7 | 54.1 | 40 | 284.3 | 0.89 | 35 | 252 | 181 | 351 | |
| Dysentery | 3 | 13,977 | 21 | 6.9 | 66.6 | 24.5 | 12 | 87.6 | 57.1 | 21 | 153.4 | 0.89 | 19 | 136 | 87 | 213 | |
| Mild diarrhea | 3 | 13,977 | 21 | 6.9 | 66.6 | 16.2 | 19 | 132.8 | 49.5 | 37 | 268.0 | 0.89 | 33 | 238 | 169 | 334 | |
| ≥5 years | Overall | 67 | 86,274 | 78 | 61.1 | 98.7 | 363 | 420.6 | 679 | 786.7 | 0.89 | 602 | 698 | 644 | 756 | ||
| Dehydration | 7 | 86,274 | 8 | 3.9 | 17.0 | 20.3 | 35 | 40.0 | 56.4 | 61 | 71.0 | 0.89 | 54 | 63 | 48 | 82 | |
| Dysentery | 24 | 86,274 | 28 | 18.6 | 41.5 | 31.6 | 76 | 88.1 | 64.5 | 118 | 136.6 | 0.89 | 105 | 121 | 100 | 147 | |
| Mild diarrhea | 36 | 86,274 | 42 | 30.1 | 57.8 | 14.3 | 252 | 292.5 | 50.5 | 500 | 579.1 | 0.89 | 443 | 514 | 468 | 564 | |
| Total | Overall | 116 | 102,217 | 113 | 94.6 | 136.1 | 864 | 845.2 | 1614 | 1578.9 | 0.90 | 1459 | 1 427 | 1 356 | 1502 | ||
| Dehydration | 39 | 102,217 | 38 | 27.9 | 52.2 | 17.2 | 227 | 222.0 | 57.8 | 393 | 384.3 | 0.90 | 355 | 347 | 313 | 386 | |
| Dysentery | 24 | 102,217 | 23 | 15.7 | 35.0 | 28.6 | 84 | 82.1 | 65.3 | 128 | 125.7 | 0.90 | 116 | 114 | 95 | 136 | |
| Mild diarrhea | 53 | 102,217 | 52 | 39.6 | 67.9 | 9.6 | 553 | 541.2 | 50.6 | 1093 | 1068.9 | 0.90 | 988 | 966 | 908 | 1029 | |
| Sex | |||||||||||||||||
| Male | Overall | 48 | 48,253 | 99 | 75.0 | 132.0 | 395 | 819.5 | 764 | 1583.6 | 0.90 | 689 | 1 428 | 1 326 | 1539 | ||
| Dehydration | 14 | 48,253 | 29 | 17.2 | 49.0 | 15.6 | 90 | 185.6 | 57.5 | 156 | 322.9 | 0.90 | 141 | 291 | 247 | 344 | |
| Dysentery | 9 | 48,253 | 19 | 9.7 | 35.8 | 29.7 | 30 | 62.9 | 64.3 | 47 | 97.8 | 0.90 | 43 | 88 | 65 | 119 | |
| Mild diarrhea | 25 | 48,253 | 52 | 35.0 | 76.7 | 9.1 | 276 | 571.0 | 49.1 | 561 | 1162.9 | 0.90 | 506 | 1 049 | 961 | 1144 | |
| Female | Overall | 68 | 53,964 | 126 | 99.4 | 159.8 | 465 | 862.0 | 845 | 1565.5 | 0.91 | 766 | 1 420 | 1 323 | 1524 | ||
| Dehydration | 25 | 53,964 | 46 | 31.3 | 68.6 | 18.8 | 133 | 245.9 | 58.0 | 229 | 424.0 | 0.91 | 208 | 385 | 3356 | 441 | |
| Dysentery | 15 | 53,964 | 28 | 16.8 | 46.1 | 27.9 | 54 | 99.8 | 66.1 | 81 | 151.0 | 0.91 | 74 | 137 | 109 | 172 | |
| Mild diarrhea | 28 | 53,964 | 52 | 35.8 | 75.1 | 10.1 | 279 | 516.2 | 52.1 | 534 | 990.5 | 0.91 | 485 | 898 | 822 | 982 | |
Incidence rates (IR) per 100,000 PYO.
Adjustment 1 based on percentage of patients who met sample collection criteria who provided a stool sample (see Methods).
Adjustment 2 (total adjustment) based on the patients with diarrhea or dysentery during home visit, who visited the field clinic (adjusting the adjustment 1 rates—see methods).