Figure 1. Experimental overview.

A) Samples from this study are depicted along a timeline with day 0 representing the day of AML diagnosis. B) Data types generated for each sample are indicated along with a basic summary of their dependencies. C) A depiction of the analysis strategies employed, their outputs and the datasets they rely on are depicted as a schematic ‘subway map’. Refer to Supplemental Experimental Procedures for additional methods and results associated with each.