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. 2015 Dec 3;11:295. doi: 10.1186/s12917-015-0610-7

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© Cortese et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The combination of the pharmacological treatment with an immune-modulating diet restores Treg percentage and count in sick dogs. Panel A and B show the percentage and count (x10⁻⁶/L), respectively, of Foxp3 + CD4 + CD3+ (Treg) cells in healthy dogs, in sick dogs at T0, T3, T6 and T12 in SD Group (pharmacological treatment alone) and IMMD Group (pharmacological treatment and immune-modulating diet), as indicated. The column of Healthy Dogs refers to the means ± SD values of normal range (see material and methods) of Treg measurements in healthy controls. Results were considered significant at p < 0.05