Figure 1.

AA enhances skin wound-healing effect of hUCB-MSCs. Two 6-mm wounds were made on the back of each ICR mouse, where we treated vehicle, AA, hUCB-MSCs + vehicle, and hUCB-MSCs + AA by topical application and intradermal injection. (a) Representative images of mouse cutaneous wounds on postoperative days are shown. (b) Open wound areas relative to the original wound size were quantified by using Image J program. (c) Representative images of neovasculature in wounds at day 9. Vessel densities relative to the group treated with vehicle alone were quantified by using Image J program (lower panel). (d) Representative H&E sections of wound tissues at day 9 are shown. (e) Hair follicle densities relative to the group treated with vehicle alone were quantified. (a–e) n=5. Error bars represent the mean ±S.E. *P<0.05, **P<0.01. Scale bars=100 μm