Table 2. Thirty-four effective drugs were classified into six different functional groups.
| Function | Drug name |
PubMed search |
Experiment |
||
|---|---|---|---|---|---|
| Brain cancer | Other cancers | MTT IC50 (μM) | Clonogenic IC50 (μM) | ||
| Anti-inflammation | Tanespimycin | V | V | <0.1 | ND |
| 15-delta prostaglandin J2 | V | V | >10 | <10 | |
| Luteolin | V | V | <10 | <10 | |
| Parthenolide | V | V | 5~10 | <10 | |
| Antibiotics | Thiostrepton | V | V | <1 | ND |
| Antimycin A | V | V | <1 | <10 | |
| Sulconazole | N/A | N/A | >10 | <10 | |
| Cycloserine | V | V | <10 | ND | |
| Antipsychotics | Chlorpromazine | V | V | 5~10 | <3.3 |
| Trifluoperazine | V | V | >10 | <1 | |
| Thioridazine | V | V | 5~10 | <10 | |
| Prochlorperazine | V | V | >10 | <10 | |
| Fluphenazine | V | V | 5~10 | ND | |
| Perphenazine | V | V | 5~10 | <10 | |
| Cardiovascular drugs | Piperlongumine | V | V | <1 | ND |
| Propafenone | N/A | V | >10 | <10 | |
| Phenoxybenzamine | V | V | >10 | <10 | |
| Amiodarone | V | V | >5 | ND | |
| Chemotherapeutic drugs | Daunorubicin | V | V | <1 | ND |
| Camptothecin | V | V | <0.1 | <10 | |
| Thioguanosine | V | V | <5 | ND | |
| 8-azaguanine | V | V | <10 | ND | |
| GW-8510 | N/A | V | <3 | ND | |
| Ellipticine | V | V | <1 | ND | |
| Others | Cloperastine | N/A | N/A | >10 | <10 |
| Nitrarine dihydrochloride | N/A | N/A | >10 | <10 | |
| Emetine | V | V | <0.1 | ND | |
| Tyloxapol | N/A | V | 5~10 | ND | |
| Norcyclobenzaprine | N/A | N/A | >10 | <10 | |
| Trichostatin A | V | V | <0.33 | ND | |
| Pyrvinium | N/A | V | <0.1 | ND | |
| Bepridil | V | V | 5~10 | ND | |
| Verteporfin | N/A | V | <3.3 | ND | |
| Vorinostat | V | V | <1 | ND | |
Abbreviations: ‘N/A', no evidence linked to cancer in PubMed; ‘ND', not determined