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Envelope precursor and defense levels in cross-linked proteome. (a and b). Level of early envelope, late envelope, filaggrin-related proteins and envelope defense proteins in the cross-linked proteome. Epidermal scale and cornified material was collected and processed as described in the legend to Figure 3. The values are spectral units shown as the mean±S.D. The asterisks indicate a significant difference (P<0.001, n=3)
