Figure 1.

The ratios of enrichment of 5mC and 5hmC at exon 2 of POLGA and mtDNA copy number. (a) 5mC/5hmC ratios in cancer and transformed cells. (b) mtDNA copy number in cancer and transformed cells. (c) 5mC/5hmC in pluripotent/multipotent cells and endometrial tissue. (d) mtDNA copy number in pluripotent/multipotent cells and endometrial tissue. (e) 5mC/5hmC in terminally differentiated/post-mitotic tissues/cells. (f) mtDNA copy number in terminally differentiated/post-mitotic tissues/cells. (g) mtDNA copy number over ratios of 5mC/5hmC for all three categories of cells. (h) POLGA expression over ratios of 5mC/5hmC for all three categories of cells. Significance: *P<0.05; **P<0.01; ***P<0.001