Table 1. Correlation between p-PAK1 expression and patient characteristics.
Characteristic | Patients (n=119) | p-PAK1 expression | P-valuea | ||
---|---|---|---|---|---|
Number | % | High (n=59) | Low (n=60) | ||
Age (years) | 0.634 | ||||
≤60 | 51 | 42.9 | 24 | 27 | |
>60 | 68 | 57.1 | 35 | 33 | |
Gender | 0.103 | ||||
Male | 74 | 62.2 | 41 | 33 | |
Female | 45 | 37.8 | 18 | 27 | |
ECOG PS | 0.506 | ||||
0 | 50 | 42.0 | 23 | 27 | |
≥1 | 69 | 58.0 | 36 | 33 | |
Tumor size (cm) | <0.001 | ||||
≤4 | 53 | 44.5 | 12 | 41 | |
>4 | 66 | 55.5 | 47 | 19 | |
TNM stage | <0.001 | ||||
I | 80 | 67.2 | 25 | 55 | |
II | 10 | 8.4 | 8 | 2 | |
III | 22 | 18.5 | 19 | 3 | |
IV | 7 | 5.9 | 7 | 0 | |
Tumor thrombus | 0.013 | ||||
No | 113 | 95.0 | 53 | 60 | |
Yes | 6 | 5.0 | 6 | 0 | |
Fuhrman grade | 0.002 | ||||
1 | 42 | 35.3 | 17 | 24 | |
2 | 52 | 43.7 | 21 | 31 | |
3 | 20 | 16.8 | 15 | 5 | |
4 | 5 | 4.2 | 6 | 0 | |
Necrosis | 0.001 | ||||
Absent | 55 | 46.2 | 18 | 37 | |
Present | 64 | 53.8 | 41 | 23 |
Abbreviations: p-PAK1, phospho-p21-activated kinase 1; ECOG PS, Eastern Cooperative Oncology Group performance status
T-test for continuous variables and χ2 test or Fisher's exact test for categorical variables. Bold values indicate P<0.05
P<0.05 is considered statistically significant