Table 1. Top molecular pathways deregulated in shNFAT1 knocked down cells.

Molecular and cell function	Significance
Cellular movement	3.00 × 10−8
Cell death and survival	1.94 × 10−7
Cellular development	2.88 × 10−7
Cellular growth and proliferation	2.88 × 10−7
Cellular function and maintenance	3.47 × 10−5

The 325 genes that showed an at least twofold expression change between control and shNFAT1 samples were submitted to pathway analysis using the Ingenuity Pathways Analysis (IPA).