Table 1. IC50 values were estimated after 24 h treatment with UNBS1450 on the same panel of cell models as in Figures 1c and d.
Cell line | IC50 24 h (nM) |
---|---|
U937 | 17.8±1.0 |
Raji | 40.2±3.7 |
K562 | 32.7±3.1 |
Jurkat | 15.6±0.7 |
PC3 | 51.0±17.0 |
DU145 | 21.0±3.0 |
A549 | 32.0±3.0 |
SH-SY5Y | 28.4±0.4 |
S-K-NAS | 48.7±4.9 |
BE(2)-M17 | 51.0±2.0 |
The impact of UNBS1450 on cell metabolism/viability was evaluated by Cell Titer-Glo assay. Values are the mean of three independent experiments±S.D.