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. 2015 Jun 11;6(6):e1781. doi: 10.1038/cddis.2015.148

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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ΔNp63α rescues reduction in VD₃-mediated cell proliferation following loss of VDR. (a) The expression of eGFP and ΔNp63α were confirmed in HaCaT-eGFP and HaCaT-ΔNp63α stable cells via immunoblot analysis. (b) HaCaT-eGFP and HaCaT-ΔNp63α stable pools were transfected with non-silencing control (NSC) or siVDR followed by treatment with vehicle control, 10 nM or 100 nM VD₃ for 24 h. Cell viability was measured following VD₃ treatment by trypan blue cell exclusion. Error bars represent standard deviation from the mean. *P values≤0.05 compared with vehicle control EGFP expressing HaCaT cells. ^#P values≤0.05 compared with 10 nM EGFP expressing HaCaT cells