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Peripapillary retinal nerve fiber layer (PRNFL) thickness at baseline and after induction of pNAION followed within 15 minutes by an intravitreal injection of either ranibizumab (Lucentis) or sterile saline (vehicle). Note that both the rate and the degree of thickening and subsequent thinning of the PRNFL are similar in the two eyes of all four animals (A1, O1, J1, S1).
