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. 2015 Aug 20;1(6):664–677. doi: 10.1016/j.jcmgh.2015.08.003

Figure 1.

Figure 1

Sleep disruption and Western diet alter food intake and liver and white adipose tissue weight. (A) Average body weight of control and sleep-disrupted (SD) mice on chow or Western diet (WD). (B) Average daily food intake was significantly increased during sleep disruption in chow-fed mice and was reduced in Western diet–fed mice undergoing sleep disruption. (C) Wet liver weight from each mouse was normalized to total body weight. Sleep disruption significantly increased liver weight in mice maintained on both chow and Western diet. (D) White adipose tissue weight (normalized to body weight) did not differ significantly due to sleep disruption in mice maintained on chow diet, but was significantly increased in mice maintained on Western diet. Data were pooled from chow-fed control (n = 36) and sleep-disrupted (n = 34) mice, and from Western diet-fed control (n = 24) and sleep-disrupted (n = 24) mice across all time points measured. White bar, control; black bar, sleep disrupted. Data were analyzed by one-way analysis of variance. aP < .05 within control treatment; bP < .05 with Western diet; cP < .05 within sleep disruption treatment.