Cut-off (m/s)	AUROC	Sensitivity (%)	Specificity (%)	+LR	-LR	PPV (%)	NPV (%)
F1	1.14	0.759	71,85	87,50	5,75	0,32	99,5	8,4
F2	1.22	0.683	67,94	63,77	1,88	0,50	85,0	39,6
F3	1.71	0.729	51,14	86,32	3,74	0,57	63,4	79,2
F4	1.77	0.855	80,77	82,54	4,63	0,23	32,3	97,7

For the calculated optimal cut-off, VTIQ had very good positive predictive value for the presence of any fibrosis (F1-F4), even if a high overlap rate was observed in pts with F0, F1 and F2. VTIQ also had a good negative predictive value for cirrhosis (table).