Table 1.
Participant Demographics
| Participant | Group | Threshold Type | Motor Threshold (% of Machine Output) | Sex | Age (y) | GMFCS | MACS | Stroke Hemisphere | Stroke Location |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MEP | RMT | 39 | F | 15 | 1 | 1 | R | PVWM |
| 2 | MEP | RMT | 42 | F | 15 | 1 | 2 | L | LV, BG |
| 3 | MEP | RMT | 72 | M | 8 | 1 | 2 | L | T, P, posterior/anterior IC |
| 4 | MEP | RMT | 65 | M | 8 | 1 | 2 | L | T, P, BG, anterior IC, |
| 5 | MEP | RMT | 79 | M | 8 | 1 | 1 | L | MCA, CS, parietal/occipital/ frontal WM |
| 6 | MEP | AMT | 79 | M | 8 | 1 | 2 | L | T, P, BG, anterior IC |
| 7 | MEP | AMT | 74 | M | 8 | 1 | 2 | L | PFL |
| 8 | MEP | AMT | 66 | M | 12 | 1 | 2 | R | CS, BG, T |
| 9 | MEP | RMT | 69 | F | 12 | 1 | 2 | L | BG, MCA, PFL T |
| 10 | MEP | AMT | 78 | F | 8 | 1 | 2 | R | CR, PFL |
| 11 | MEP | AMT | 60 | M | 9 | 1 | 2 | L | IC, T, P, LN,CR |
| 12 | MEP | AMT | 85 | M | 11 | 1 | 2 | L | FPC, IC, T, BG |
| 13 | MEP | AMT | 52 | F | 8 | 1 | 2 | L | C, CS, IC, T, PFL |
| 14 | MEP | RMT | 84 | M | 15 | 1 | 2 | L | CR, T, BG |
| 15 | MEP | AMT | 52 | M | 15 | 1 | 1 | R | MCA |
| 16 | MEP | AMT | 81 | F | 10 | 1 | 3 | L | MCA |
| 17 | MEP | RMT | 63 | F | 10 | 1 | 2 | R | PFL |
| 18 | MEP | RMT | 68 | F | 14 | 1 | 1 | R | PFL |
| 19 | MEP | RMT | 46 | F | 13 | 1 | 2 | L | PFL, parietal/occipital lobes, BG, T |
| 20 | no-MEP | none | none | F | 8 | 1 | NA | L | PVWM, parieto-occipal cortex |
| 21 | no-MEP | none | none | F | 8 | 1 | NA | L | LV |
| 22 | no-MEP | none | none | M | 9 | 1 | NA | R | MCA |
| 23 | no-MEP | none | none | M | 16 | 1 | NA | R | BG, C, PFL |
| 24 | no-MEP | none | none | M | 13 | 1 | NA | R | R hemisphere rostral to midbrain |
| 25 | no-MEP | none | none | F | 10 | 1 | NA | L | CR, T, PFL |
| 26 | no-MEP | none | none | M | 9 | 1 | NA | L | MCA |
| 27 | no-MEP | none | none | M | 8 | 1 | NA | L | parietal/occipital lobes |
| 28 | no-MEP | none | none | F | 9 | 1 | NA | R | BG, CS, FL, T |
| 29 | no-MEP | none | none | M | 8 | 1 | NA | L | BG, CS, MCA, FPC, IC, T |
| 30 | no-MEP | none | none | M | 8 | 2 | NA | L | CS, FPC |
| Participant | Group | M1 I/C Volume Ratio | PLIC I/C Volume Ratio | AI (%) Affected | AI (%) Less Affected | AHA Score (Logit-Based) | Mirroring |
|---|---|---|---|---|---|---|---|
| 1 | MEP | 0.863 | 0.995 | 68.23 | 73.33 | 100 | No |
| 2 | MEP | 0.839 | 0.889 | 57.10 | 64.07 | 86 | No |
| 3 | MEP | 0.918 | 0.831 | −41.03 | −40.07 | 48 | Yes |
| 4 | MEP | 0.829 | 0.403 | −13.67 | 40.83 | 35 | Yes |
| 5 | MEP | 0.986 | 0.980 | 43.50 | 64.10 | 90 | No |
| 6 | MEP | 0.830 | 0.415 | 27.30 | 48.43 | 63 | Yes |
| 7 | MEP | 0.462 | 0.898 | 66.23 | 65.10 | 67 | No |
| 8 | MEP | 0.870 | 0.681 | 53.13 | 70.87 | 66 | Yes |
| 9 | MEP | 0.301 | 0.488 | −64.30 | 73.10 | 46 | Yes |
| 10 | MEP | 0.640 | 0.789 | 46.40 | 29.23 | 67 | No |
| 11 | MEP | 0.858 | 1.110 | −15.63 | 54.00 | 54 | No |
| 12 | MEP | 0.820 | 0.778 | 7.77 | 68.63 | 59 | No |
| 13 | MEP | 0.578 | 1.022 | −52.37 | 36.23 | 57 | Yes |
| 14 | MEP | 1.070 | 0.777 | 1.40 | 42.60 | 66 | Yes |
| 15 | MEP | 0.416 | 0.753 | 57.83 | 78.47 | 55 | Yes |
| 16 | MEP | 0.526 | 0.632 | −17.72 | 43.00 | 45 | Yes |
| 17 | MEP | 1.070 | 0.707 | 42.33 | 64.20 | 71 | Yes |
| 18 | MEP | 1.130 | 0.722 | −3.83 | MD | 48 | No |
| 19 | MEP | 0.516 | 0.763 | 53.67 | 72.53 | 73 | No |
| 20 | no-MEP | 0.761 | 0.649 | −8.67 | −25.17 | NA | No |
| 21 | no-MEP | 0.106 | 0.161 | 2.07 | 21.03 | NA | Yes |
| 22 | no-MEP | 0.373 | 0.139 | −0.27 | 6.30 | NA | Yes |
| 23 | no-MEP | 0.675 | 0.536 | 44.37 | 72.76 | NA | Yes |
| 24 | no-MEP | 0.000 | 0.137 | −49.70 | 27.23 | NA | Yes |
| 25 | no-MEP | 0.847 | 0.581 | 39.63 | 49.53 | NA | Yes |
| 26 | no-MEP | 0.579 | 0.051 | 31.87 | 49.97 | NA | No |
| 27 | no-MEP | 0.436 | 0.564 | MD | MD | NA | MD |
| 28 | no-MEP | 0.228 | 0.032 | 36.13 | 40.90 | NA | No |
| 29 | no-MEP | 0.554 | 0.597 | −54.27 | −7.90 | NA | No |
| 30 | no-MEP | 0.983 | 1.058 | −6.63 | −10.07 | NA | No |
AMT active motor threshold, BG basal ganglia, C caudate, CR corona radiata, CS centrum semiovale, F female, FL frontal lobe, FPC frontoparietal cortex, GMFCS Gross Motor Function Classification Scale, GP globus pallidus, IC internal capsule, L left, LN lentiform nucleus, LV adjacent to lateral ventricle, M male, MACS Manual Abilities Classification Scale, MCA middle cerebral artery distribution, MEP ipsilesional motor-evoked potential, NA not available, no-MEP absent ipsilesional motor-evoked potential, P putamen, PFL posterior frontal lobe, PVWM periventricular white matter, R right, RMT resting motor threshold, T thalamus, WM white matter, y years
AHA Assisting Hand Assessment (Logit-Based Scores), AI accuracy index, I/C ipsilesional/contralesional, M1 primary motor cortex, MD missing data, MEP motor-evoked potential, NA not available, no-MEP absent ipsilesional motor-evoked potential, PLIC posterior limb of internal capsule