Table 2.

Clinical outcomes and temporal trends.

	Event Rate
Event	Overall	0–30 days	Month 1–12	12 month – 4 year
ISCHEMIC ENDPOINT
Cardiovascular death, non-periprocedural myocardial infarction or definite/probable stent thrombosis	1.64%/yr 0.14%/mo (6.51%)*	10.76%/yr 0.90%/mo (0.89%)*	1.42%/yr 0.12%/mo (1.29%)*	1.44%/yr 0.12%/mo (4.40%)*
Cardiovascular death	0.91%/yr 0.08%/mo (3.69%)	5.24%/yr 0.44%/mo (0.44%)*	0.82%/yr 0.07%/mo (0.75%)*	0.88%/yr 0.07%/mo (2.72%)*
Non-periprocedural myocardial infarction	0.87%/yr 0.07%/mo (3.52%)*	5.24%/yr 0.44%/mo (0.44%)*	1.10%/yr 0.09%/mo (1.00%)*	0.69%/yr 0.06%/mo (2.11%)*
Definite/probable stent thrombosis	0.51%/yr 0.04%/mo (2.06%)*
Acute		34.45%/yr 2.87%/mo (0.10%)*	N/A	N/A
Subacute		8.47%/yr 0.71%/mo (0.68%)*	N/A	N/A
Late		N/A	0.31%/yr 0.03%/mo (0.29%)*	N/A
Very late		N/A	N/A	0.37%/yr 0.03%/mo (1.14%)*
BLEEDING ENDPOINT
GUSTO Moderate/Severe bleeding	0.75%/yr 0.06%/mo (3.03%)*	8.19%/yr 0.68%/mo (0.68%)*	1.08%/yr 0.09%/mo (0.98%)*	0.44%/yr 0.04%/mo (1.36%)*
Moderate	0.40%/yr 0.03%/mo (1.64%)*	2.94%/yr 0.24%/mo (0.24%)*	0.64%/yr 0.05%/mo (0.59%)*	0.26%/yr 0.02%/mo (0.82%)*
Severe	0.34%/yr 0.03%/mo (1.39%)*	5.24%/yr 0.44%/mo (0.44%)*	0.57%/yr 0.05%/mo (0.52%)*	0.17%/yr 0.01%/mo (0.54%)*

^*Absolute rate