Table 3.
Multivariable predictors for ischemic and bleeding endpoints
| ISCHEMIC ENDPOINT | BLEEDING ENDPOINT | |||
|---|---|---|---|---|
|
| ||||
| Optimism-corrected odds ratio | 95% confidence interval | Optimism-corrected odds ratio | 95% confidence interval | |
|
| ||||
| Age, per 10 years | 1.37 | 1.25 – 1.50 | 1.38 | 1.22 – 1.56 |
|
| ||||
| Male | 1.36 | 1.12 – 1.66 | – | – |
|
| ||||
| BMI, per kg/m2 | 1.03 | 1.01 – 1.04 | – | – |
|
| ||||
| Active smoking | 1.49 | 1.22 – 1.81 | 1.34 | 1.03 – 1.75 |
|
| ||||
| Diabetes mellitus | 1.77 | 1.50 – 2.09 | 1.24 | 1.00 – 1.55 |
|
| ||||
| Prior MI | 1.47 | 1.23 – 1.76 | – | – |
|
| ||||
| Prior CABG | 1.41 | 1.06 – 1.87 | – | – |
|
| ||||
| Prior CHF | 1.75 | 1.27 – 2.39 | 1.73 | 1.15 – 2.60 |
|
| ||||
| Creatinine clearance, mL/min | ||||
| ≥ 60 | Reference | Reference | Reference | Reference |
| 30–59 | 1.93 | 1.55 – 2.41 | 1.61 | 1.23 – 2.11 |
| < 30 | 5.41 | 3.14 – 9.32 | 2.79 | 1.43 – 5.41 |
| Missing | 1.61 | 1.19 – 2.18 | 0.56 | 0.30 – 1.07 |
|
| ||||
| Presentation | ||||
| Stable angina | Reference | Reference | – | – |
| NSTEACS | 1.14 | 0.96 – 1.35 | ||
| STEMI | 1.71 | 1.29 – 2.26 | ||
|
| ||||
| Zotarolimus-eluting stent | 0.80 | 0.68 – 0.93 | – | – |
|
| ||||
| Total stent length, per 10 mm | 1.07 | 1.03 – 1.10 | – | – |
BMI, body-mass index; MI, myocardial infarction; CABG, coronary artery bypass graft surgery; CHF, congestive heart failure; NSTEACS, non-ST elevation acute coronary syndrome; STEMI, ST elevation myocardial infarction