Fig 6. Timing and spatial differences of the NR2A/2B developmental switch.

In human cortex (RNA-seq:A, microarrays: D) and Hippocampus (RNA-seq:B; microarrays:E) childhood expression level of NR2B exhibit little significant change, and NR2A may be rising slowly. In the cerebellum (RNA-seq: C; microarrays: F), a more significant switch is observed. In all cases, the largest changes in expression levels occur before birth, and much smaller changes are observed postnatally.