Table 1. Down-regulated genes with predicted oxidoreductase activity (GO:0055114 'oxidation reduction' and/or GO:0016491 'oxidoreductase activity').
| Closest structural homolog in the Protein Data Bank | ||||||||
|---|---|---|---|---|---|---|---|---|
| Accession no. (GL50803) | Genome annotation | Species | Protein name | PDB code | TM score | RMSD (Å) | % AA identity | % Coverage |
| 14759 | 6-phosphogluconate dehydrogenase, decarboxylating | |||||||
| 13350 | Alcohol dehydrogenase lateral transfer candidate | |||||||
| 7260 | Aldose reductase | |||||||
| 15460 | Dynein-like protein | |||||||
| 7195 | Glutamate synthase* | Methylophilus methylotrophus | Trimethylamine dehydrogenase | 1DJQ | 0.7084 | 1.41 | 10.0 | 71.86 |
| 6175 | Nitroreductase 1** | |||||||
| 88581 | Synaptic glycoprotein SC2 | |||||||
| 9068 | Hypothetical protein | Thermus thermophilus | Cytochrome c oxidase polypeptide i+iii | 2YEV | 0.7059 | 2.72 | 12.1 | 90.91 |
| 15154 | Hypothetical protein | Streptococcus pyogenes | Dps-like peroxide resistance protein | 2WLA | 0.6592 | 2.42 | 11.4 | 75.12 |
| 4690 | Hypothetical protein | Legionella pneumophila | Effector protein B | 4JW1 | 0.8506 | 1.61 | 7.5 | 91.62 |
| 87577 | Hypothetical protein | Azospirillum brasilense | Glutamate synthase [NADPH] small chain | 2VDC | 0.9178 | 2.07 | 14.1 | 98.68 |
| 15445 | Hypothetical protein | Megathura crenulata | Hemocyanin KLH1 | 4BED | 0.8475 | 2.43 | 12.8 | 95.45 |
| 17278 | Hypothetical protein | Megathura crenulata | Hemocyanin KLH1 | 4BED | 0.7172 | 3.43 | 5.6 | 87.54 |
| 29796 | Hypothetical protein | Megathura crenulata | Hemocyanin KLH1 | 4BED | 0.7377 | 3.19 | 8.7 | 82.69 |
| 4692 | Hypothetical protein | Megathura crenulata | Hemocyanin KLH1 | 4BED | 0.8456 | 2.56 | 10.6 | 98.74 |
| 14921 | Hypothetical protein | Candidatus kuenenia stuttgartiensis | Hydroxylamine oxidoreductase | 4N4J | 0.8553 | 2.94 | 10.3 | 93.57 |
| 27887 | Hypothetical protein | Bacillus subtilis | Methylthioribose-1-phosphate isomerase | 2YVK | 0.6671 | 2.73 | 9 | 92.86 |
| 15599 | Hypothetical protein | Homo sapiens | Neuronal acetylcholine receptor subunit α7 | 2MAW | 0.6878 | 1.68 | 8.1 | 75.00 |
| 88556 | Hypothetical protein | Homo sapiens | Otu domain-containing protein 5 | 3TMP | 0.4592 | 2.11 | 14.3 | 49.09 |
| 17400 | Hypothetical protein | Saccharomyces cerevisiae | Pho85 cyclin Pho80 | 2PK9 | 0.6544 | 1.89 | 13.3 | 69.11 |
| 17375 | Hypothetical protein | Vitis vinifera | Polyphenol oxidase, chloroplast | 2P3X | 0.7217 | 3.04 | 13.4 | 82.60 |
| 3951 | Hypothetical protein | Saccharomyces cerevisiae | Protein disulfide-isomerase | 3BOA | 0.8572 | 1.98 | 12.5 | 92.36 |
| 103988 | Hypothetical protein | Neisseria meningitidis | Putative uncharacterized protein | 3VJZ | 0.5651 | 3.83 | 12.3 | 82.26 |
| 11341 | Hypothetical protein | Vibrio parahaemolyticus | Sensor protein | 3I9Y | 0.7838 | 1.9 | 7.9 | 96.20 |
| 8048 | Hypothetical protein | Escherichia coli, homo sapiens | Soluble cytochrome b562 and glucagon receptor | 4L6R | 0.816 | 2.73 | 7.7 | 90.02 |
| 3581 | Hypothetical protein | Streptomyces coelicolor | Superoxide dismutase [Ni] | 3G4X | 0.7515 | 1.94 | 8.8 | 85.07 |
| 5810 | Hypothetical protein | Psychrobacter arcticus | Uncharacterized protein | 2RE7 | 0.8112 | 1.92 | 16.1 | 94.66 |
| 11129 | Hypothetical protein | Homo sapiens | Uncharacterized protein Kiaa0174 | 3FRR | 0.5589 | 1.51 | 12.6 | 57.78 |
| 10244 | Deprecated | Helicobacter pylori | Cag pathogenicity island protein (Cag18) | 3ZCI | 0.6398 | 2.86 | 4.2 | 84.43 |
| 14932 | Deprecated | Zea mays | Histidine-containing phosphotransfer protein | 1WN0 | 0.7383 | 2.39 | 16.4 | 87.01 |
| 35700 | Deprecated | Listeria monocytogenes | Lmo 0438 protein | 2XL4 | 0.7886 | 1.74 | 6.1 | 98.00 |
| 37288 | Deprecated | Vibrio cholerae | Thiol:disulfide interchange protein DsbA | 2IJY | 0.5567 | 2.92 | 3.5 | 82.26 |
Structural homology information not determined for annotated ORFs.
* Annotated glutamate synthase disambiguated from GL50803_87577 by structural homology searching
** Referred to as NR-2 by Müller et al [86].