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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Lancet Oncol. 2015 Jul 14;16(8):957–966. doi: 10.1016/S1470-2045(15)00004-2

Table 2. Surgical results.

Group 1 (n=60) Group 2 (n=67) Group 3 (n=67) Group 4 (n=65) p value
Time from start of chemoradiation to surgery (weeks) 14.2 (4.3) 17.1 (2.9) 21.0 (27) 25.2 (4.0) 0.0001

Time from end of chemoradiation to surgery (weeks) 8.5 (4.2) 11.1 (2.9) 15.4 (2.6) 19.3 (4.2) 0.0001

Sphincter-saving surgery 46 (77%) 50 (75%) 50 (75%) 44 (68%) 0.68
 Ileostomy 38/46 (83%) 43/50 (86%) 47/50 (94%) 38/43 (88%)* 0.33

Resection with negative margins 59 (98%) 67 (100%) 64 (96%) 64 (100%) 0.089

Number of nodes examined 12 (2–31) 14 (2–30) 13 (2–30) 11 (1–47) 020

Pelvic fibrosis 24 (17) 3.9 (2.6) 4.4 (2.4) 3.9 (2.4) 0.0001

Technical diffi culty§ 4.6 (27) 4.9 (2.8) 5.1 (2.5) 4.8 (2.4) 0.80

Estimated blood loss (mL) 200 (50–1200) 225 (25–1500) 200 (50–1000) 150 (0–1000) 0.62

Data are mean (SD), number (%), n/N (%), or median (range). p values test the null hypothesis of equal means or proportions across study groups.

*

Information on whether an ileostomy was created or not was not available for one patient.

Data missing for one patient.

Scale ranges from 1 (none) to 10 (maximum).

§

Scale ranges from 1 (easy) to 10 (difficult).