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. Author manuscript; available in PMC: 2016 Aug 27.
Published in final edited form as: Cell. 2015 Aug 27;162(5):1113–1126. doi: 10.1016/j.cell.2015.08.007

Figure 3. Schematic of nucleic acid recognition by SaCas9.

Figure 3

SaCas9 residues that interact with the sgRNA and the target DNA via their main chain are shown in parentheses. Water-mediated hydrogen-bonding interactions are omitted for clarity.