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Real time quantitative PCR gene expression of mediators involved in human endometrial carcinogenesis. Uterine carcinomas in TBBPA-exposed animals averaged a 30 fold overexpression of Her2 compared to a 2-fold increase in spontaneous uterine carcinomas. Uterine carcinomas from control and TBBPA-exposed animals overexpressed Ccnd1 and Cdh1, although the fold increase in expression was not significantly different between tumors.
