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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Gene Ther. 2015 Jun 30;22(12):993–999. doi: 10.1038/gt.2015.68

Scheme 1. Predicted Folded Structure of UTR mRNA.

Scheme 1

Panel A illustrates the predicted stem-loop structure of tailed UTR mRNA. The structure of (Acr-Lys4)3-Acr-Lys-Cys-PEG5kDa (peptide 1) and PEG5kDa-Cys-Trp-Lys20 (peptide 2) used to form mRNA polyplexes are shown. Acr refers to a Lys residue modified with acridine on the ε-amine.