Table 1.
Health problems across the lifespan whose onset and/or course may be affected by early adversity and subsequent activation of the proposed neuro-immune network
| Health Problem | Early Adversity and Onset and/or Course |
Inflammation’s Role in Pathogenesis |
|---|---|---|
| Early – Middle Childhood | ||
| Asthma | (21, 119, 120) | (114) |
| Respiratory Infection | (121–122) | (123) |
| Adolescence – Early Adulthood | ||
| Depression | (88, 124, 125) | (79) |
| Substance Misuse | (126–128) | (129–130) |
| Obesity | (131–132) | (104) |
| Insulin Resistance | (133–135) | (136) |
| Preclinical Atherosclerosis | (137–138) | (139) |
| Middle – Later Adulthood | ||
| Metabolic Syndrome | (117, 140–141) | (142) |
| Stroke | (143–145) | (142) |
| Coronary Heart Disease | (139, 143, 145, 146) | (142) |
| Selected Cancers | (93, 147, 148) | (115) |
| Autoimmune Conditions | (149, 150) | (14) |
Note. Because of space limitations, we are unable to cite many relevant studies here. Instead, we cite exemplar studies and definitive reviews. We apologize to authors whose work was omitted.