. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: Mol Oral Microbiol. 2015 Jul 7;31(2):136–161. doi: 10.1111/omi.12111

Table 5.

Mean fold changes in expression of S. gordonii genes following co-incubation with C. albicans.

Gene^*	Mean fold change (log₂)¹	Description²	Total abundance (log₁₀)³	P-value⁴
*glpK*	1.92	Glycerol kinase	−1.612	0.030 ^*
*SGO_0149*	1.91	Hypothetical protein	−2.812	0.135
*SGO_0092*	1.85	Hypothetical protein	0.000	0.181
*SGO_0093*	1.81	Hypothetical protein	0.000	0.123
*SGO_0631*	1.78	α-glyerophosphae oxidase	−0.955	0.101
*SGO_1071*	1.67	Hypothetical protein	−0.961	0.146
*adk*	1.56	Adenylate kinase	−1.587	0.100
*xpt*	1.49	Xanthine phosphoribosyltransferase	−1.144	0.318
*rpoA*	1.48	DNA-directed RNA polymerase	−0.282	0.133
*SGO_2091*	1.37	Hypothetical proein	−2.210	0.257
*SGO_2079*	1.29	Hypothetical protein	0.000	0.690
*rplR*	1.26	50S ribosomal protein	−0.776	0.064
*SGO_1136*	1.25	Esterase superfamily protein	−2.636	0.119
*SGO_1581*	1.25	MtN3/saliva family protein	−2.511	0.091
*rpsS*	1.24	30S ribosomal protein S19	−1.088	0.069
*rplO*	1.21	Ribosomal protein	−1.086	0.014 ^*
*trpA-1*	1.18	Tryptophan synthase subunit α	0.000	0.193
*celB*	1.15	Cellobiose metabolism operon	−1.538	0.014 ^*
*rplN*	1.15	Ribosomal protein L14	−0.918	0.009 ^*
*rplB*	1.11	Ribosomal protein L2	−0.599	0.027 ^*
*SGO_0630*	1.05	Glycerol uptake facilitator protein	−1.642	0.256
*rpsE*	1.02	Ribosomal protein S5	−0.666	0.016 ^*
*ciaR*	1.00	Transcription regulator	−0.885	0.032 ^*
*SGO_1261* *(gat)*	1.00	Glutamine amidotransferase	−1.765	0.044 ^*
*rpmD*	0.98	Ribosomal protein L30	−0.961	0.011 ^*
*celA*	0.98	Cellobiose metabolism operon	−0.738	0.026 ^*
*SGO_0571*	0.97	Hypothetical protein	0.000	0.041 ^*
*rplX*	0.94	Ribosomal protein L24	−1.020	0.023 ^*
*secY*	0.92	Preprotein translocase subunit	−1.095	0.018 ^*
*SGO_1625*	0.88	Acetoin utilization	−2.511	0.045 ^*
*SGO_1579*	0.85	Transcription antiterminator (BglG family)	−0.745	0.011 ^*
*celD*	0.80	Cellobiose metabolism operon	−0.775	0.010 ^*
*rplF*	0.80	Ribosomal protein L6	−1.062	0.039 ^*
*celC*	0.67	Cellobiose metabolism operon	−0.989	0.043 ^*
*SGO_0991*	−0.31	Hypothetical protein	−2.812	1.000
*SGO_0924*	−0.53	HsdD	0.000	0.921
*sodA*	−0.57	Superoxide dismutase	−0.818	0.760
*SGO_1461*	−0.62	Stress response transcriptional regulator	−2.511	0.630
*SGO_0378*	−0.64	Hypthothetical protein	−0.567	0.783
*rpmF*	−0.73	Ribosomal protein L32	−1.409	0.650
*rpmG*	−0.79	Ribosomal protein L33	−2.636	0.403
*glgP-2*	− 0.82	Maltodextrin phosphorylase	−0.913	0.043 ^*
*trx-2*	−0.83	Thioredoxin 2	−2.113	0.201
*gloA*	−0.83	Lactolylglutathione lyase	−1.454	0.347
*hutU*	−0.85	Urocanate hydratase	−2.414	0.235
*SGO_0584*	−0.85	Acetyltransferase	−1.591	0.073
*SGO_2084*	−0.86	Quinone family NAD(P)H deydrogenase	0.000	0.406
*ldh*	−0.89	Lactate dehydrogenase	−0.791	0.111
*SGO_1457*	−0.90	Hypothetical protein	−2.210	0.367
*SGO_1300*	−0.90	NADPH-dependant reductase	−2.210	0.465
*pyrB*	−0.91	Aspartate carbomyl transferase	−1.260	0.295
*gtfG*	−0.91	Glucosyltransferase	−0.943	0.151
*SGO_1301*	−0.93	Hypothetical protein	−2.812	0.322
*SGO_0194*	−0.94	Hypothetical protein	−1.958	0.265
*ftcD*	−0.96	Glutamate formiminotransferase	0.000	0.323
*SGO_0233*	−0.98	Lipoprotein	0.000	0.083
*SGO_1740*	−0.99	Integral membrane protein	−1.834	0.575
*bta*	−1.01	Bacteriocin transport accessory protein	−1.334	0.300
*SGO_1508*	−1.01	Uncharacterized	0.000	0.650
*secE*	−1.04	Preprotein translocase subunit	−2.636	0.113
*mscL*	−1.10	Mechanosensitive channel protein	−1.312	0.196
*SGO_1256*	−1.13	PyrK(dihydroorotate dehydrogenase)	−2.812	0.238
*SGO_1108*	−1.15	Uracil permease	−0.812	0.187
*SGO_1106*	−1.16	Hypthothetical protein	−1.958	0.384
*trx-1*	−1.17	Thioredoxin 1	−0.957	0.164
*SGO_1107*	−1.18	PyrR (pyrimidine regulatory protein)	−2.812	0.182
*glmS*	−1.25	Glucosamine fructose-6-phosphate aminotransferase	−1.001	0.090
*pyrd*	−1.29	Dihydroorotate dehydrogenase	−3.113	0.202
*carB*	−1.42	Carbamyl phosphate synthetase	−0.291	0.207
*pyrE*	−1.49	Orotate phosphoribosyl transferase	−2.636	0.228
*SGO_0296*	−1.50	Integral membrane protein	0.000	0.061
*SGO_1105*	−1.54	Hypothetical protein	−1.958	0.257

Positive values, up-regulated; negative values, down-regulated (log₂ ≥1.0 equivalent to ≥ twofold linear change)

Description details from the S. gordonii CH1 annotated genome sequence

Abundance reads represent the fractional expression of all targets in the genome

⁴

P-values were calculated from DESeq and adjusted P-values ≤ 0.05 were considered to be significant

Bold type significant change P ≤0.05