Table 1.

High expression of proteins defining previously proposed subtypes of glioblastoma multiforme (GBM)

	Proposed subtypes
Proteins reported to be highly expressed	Philips et al.13	Brennan et al.9	Verhaak et al.14	Motomura et al.16	Le Mercier et al.15
Epidermal growth factor receptor (EGFR)	Proliferative and Mesenchymal GBM	EGFR core	Classical GBM	Mixed	Classical like
CD44	Mesenchymal GBM		Mesenchymal GBM	Astrocyticmesenchymal, Mixed
Proto-oncogene tyrosine-protein kinase MER			Mesenchymal GBM
Isocitrate dehydrogenase 1 mutation			Proneural GBM	Oligodendrocyte precursor type (OPT)
OLIG2	Proneural GBM	PDGF core	Proneural GBM	Differentiated oligodendro- cyte type and OPT
P53			Proneural GBM	OPT	Proneural like
Platelet derived growth factor (PDGF) receptor α		PDGF core	Proneural GBM	OPT	Proneural like