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. 2015 Feb 3;36(6):2049–2060. doi: 10.1002/hbm.22755

Table 2.

Activated brain regions in children and adolescents with ADHD and a healthy comparison group for three oddball categories against a standard picture

ADHD group (N = 19) Comparison group (N = 19)
Local maxima Voxel per cluster t Local maxima Voxel per cluster t
Activation Cluster x y z x y z
Novel > Standard
R parahippocampal gyrusa (extending to hippocampus) 28 −36 −16 10694 13.30 24 −50 −8 10828 18.92
R fusiform gyrusa 36 −44 −22 10.87 34 −38 −24 10.95
R inferior temporal gyrusa 50 −56 −18 9.01
R middle temporal gyrusa 36 −80 20 8.89
L parahippocampal gyrusa (extending to hippocampus) −28 −48 −6 12.50
L fusiform gyrusa −30 −36 −20 10.81 −30 −68 −14 12.62
L middle occipital gyrusa −36 −72 −16 10.86 −34 −72 −16 12.20
R middle occipital gyrusa 38 −72 −12 10.03
L inferior occipital gyrusa −44 −60 −14 9.19
R inferior occipital gyrusa 44 −62 −16 9.59
R thalamus 20 −30 −2 10.90
L precuneus −16 −74 50 233 5.33
R superior parietal lobule (extending to angularis) 28 −68 46 125 5.06
Neutral > Standard
R fusiform gyrus/parahippocampal gyrusb 30 −60 −10 777 6.47
L fusiform gyrus/parahippocampal gyrusb −32 −52 −18 725 7.95
R cuneus 18 −90 30 184 5.66
R precuneus 1 −68 24 503 5.05
L posterior cingulate −8 −60 10 95 4.47
L middle occipital gyrusb −32 −80 14 237 5.66
Target > Standard
L postcentral gyrusa −48 −28 56 995 11.45 −46 −24 56 2474 11.33
L medial frontal gyrus (reaching in anterior cingulate) −2 −2 52 1007 7.66
R medial frontal gyrus 6 10 50 706 7.35
R anterior cingulated (extending to posterior region) 6 −18 28 268 6.30
R posterior cingulate 6 −32 24 510 7.72
R precuneus 4 −72 40 242 5.06 8 −72 40 454 7.21
L thalamus −10 −18 8 127 6.80 −12 −24 8 555 7.05
L insula −46 −4 4 472 6.60 −34 12 4 99 5.41
R insula 32 16 4 490 6.91
R superior temporal gyrus (cluster includes right insula) 46 12 4 268 6.50
R inferior parietal lobule 48 −44 44 143 6.25
L middle occipital gyrus/fusiform gyrus −36 −82 −16 299 6.15
R anterior cerebellum/culmen 28 −46 −20 1047 11.15 18 −52 −28 1139 9.36
L culmen −38 −52 −26 216 5.84

P < 0.05, cluster‐wise FDR corrected; ADHD = attention deficit hyperactivity disorder; L = left; R = right.

a

Areas that showed common activity in both groups (inclusive masking).

b

Areas that showed common activity for novel and neutral pictures in ADHD (inclusive masking).