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. 2015 Dec 4;8:83. doi: 10.1186/s13041-015-0176-0

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© Sasaki et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Neurobiological effects of D-cycloserine and nefiracetam in Hbegf cKO mice. a-c, Effects of D-cycloserine and nefiracetam on the decrease in levels of p-ERK₁, p-ERK₂, p-NR1, total NR1, NR2B and PSD-95. Schedule of drug treatments were the same as in Fig. 6a. Results represent typical pictures of western blot analysis: (a), and quantitative comparisons: (b). n = 5 (all groups). Values are the means ± s.e.m. Typical pERK_1/2-like immunohistochemical pictures in the hippocampus: (c)