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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1882–1889. doi: 10.1158/1055-9965.EPI-15-0623

Table 2.

Breast Cancer Rate per 1000 person-years by Screening Mammogram Result and Breast Density, Breast Cancer Surveillance Consortium

Prior Mammogram
Result / Recommendation
Number breast
cancer cases
Person years
at risk
Breast cancer rate
(95%CI) per 1000 P-Y
ALL WOMEN:
  True-negative 43,105 11,034,496 3.91 (3.87, 3.94)
  False-positive, additional imaging 4,742 861,365 5.51 (5.35, 5.66)
  False-positive, biopsy 888 126,699 7.01 (6.56, 7.48)
BY BI-RADS BREAST DENSITY:
ALMOST ENTIRELY FAT
  True-negative 2,206 993,559 2.22 (2.13, 2.31)
  False-positive, additional imaging 123 33,291 3.69 (3.07, 4.41)
  False-positive, biopsy 23 5,774 3.98 (2.53, 5.97)
SCATTERED FIBROGLANDULAR DENSITY
  True-negative 17,884 5,070,911 3.53 (3.37, 3.47)
  False-positive, additional imaging 1,737 355,192 4.89 (4.51, 4.95)
  False-positive, biopsy 315 52,612 5.99 (5.09, 6.36)
HETEROGENEOUSLY DENSE
  True-negative 19,014 4,143,830 4.59 (4.52, 4.65)
  False-positive, additional imaging 2,372 398,280 5.96 (5.72, 6.20)
  False-positive, biopsy 448 56,984 7.86 (7.15, 8.62)
EXTREMELY DENSE
  True-negative 4,001 826,197 4.84 (4.69, 4.99)
  False-positive, additional imaging 510 74,602 6.84 (6.26, 7.45)
  False-positive, biopsy 102 11,329 9.00 (7.35, 10.92)

BI-RADS = Breast Imaging-Reporting and Data System; CI = confidence interval; P-Y = person years