Table 1.

Decay time constants for NMDAR-mediated synaptic currents over early postnatal development.

		P15			P30			P45
		Tau (ms)	n	P	Tau (ms)	n	P	Tau (ms)	n	P
Pyramidal Neurons
Mecp2 WT	Control	116±8	12	**	70±4	11	n.s.	73±5	13	n.s.
	Ifenprodil	76±10	12		60±4	12		67±5	13
Mecp2 KO	Control	102±6	15	**	90±5	10	**	74±3	18	**
	Ifenprodil	69±8	10		71±5	8		60±4	10
Parvalbumin Interneurons
Mecp2 WT	Control	104±6	12	**	82±5	10	**	56±5	11	n.s.
	Ifenprodil	61±6	13		55±5	9		55±6	8
Mecp2 KO	Control	102±4	13	**	60±5	11	n.s.	56±4	13	n.s.
	Ifenprodil	71±5	10		48±5	9		52±4	13

Tau = Time constant of NMDAR-mediated synaptic current decay; n=number of cells;

^**P <0.01,

ANOVA with Bonferroni correction for multiple comparisons