Table 2.
Cox regression analysis of predictors of the infection end point and the rejection end point
| Variable | Infection End Point | Rejection End Point | ||
|---|---|---|---|---|
| Overall Relative Risk (95% CI) | P Value | Overall Relative Risk (95% CI) | P Value | |
| Recipient age (yr) | 1.01 (1.00 to 1.02) | 0.01 | 0.99 (0.98 to 1.00) | 0.20 |
| Women | 1.08 (0.85 to 1.38) | 0.51 | 0.92 (0.71 to 1.19) | 0.42 |
| Pretransplant diabetes mellitus | 1.12 (0.86 to 1.71) | 0.27 | 1.40 (0.97 to 2.03) | 0.07 |
| Donor type | ||||
| Living | 1.00 (reference group) | 1.00 (reference group) | ||
| Deceased not ECD | 2.15 (1.41 to 3.26) | <0.001 | 1.57 (1.05 to 2.35) | 0.03 |
| Deceased ECD | 1.69 (1.20 to 2.38) | 0.003 | 1.17 (0.84 to 1.61) | 0.35 |
| Donor age (yr) | 1.00 (0.99 to 1.02) | 0.27 | 1.00 (0.99 to 1.01) | 0.24 |
| No. of HLA mismatches | 1.08 (1.01 to 1.17) | 0.05 | 1.18 (1.08 to 1.28) | <0.001 |
| Cytomegalovirus status | ||||
| Other | 1.00 (reference group) | 1.00 (reference group) | ||
| D+/R− | 1.45 (1.08 to 1.94) | 0.01 | 0.99 (0.70 to 1.41) | 0.96 |
| Immunosuppression | ||||
| Group A | 1.00 (reference group) | 1.00 (reference group) | ||
| Group B | 0.91 (0.69 to 1.20) | 0.51 | 0.88 (0.67 to 1.15) | 0.34 |
| Group C | 0.82 (0.62 to 1.09) | 0.17 | 0.46 (0.33 to 0.63) | <0.001 |
95% CI, 95% confidence interval; ECD, extended criteria donor; D+/R−, donor seropositive and recipient seronegative.