Table 1.
Characteristics of hemodialysis initiates (N=324), by frailty status
| Characteristic | Nonfrail (n=92) | Intermediately Frail (n=122) | Frail (n=110) | P Value |
|---|---|---|---|---|
| Women | 45.7 | 38.5 | 47.3 | 0.37 |
| Age (yr) | 52.0 (11.7) | 54.8 (14.1) | 57.0 (13.3) | 0.03 |
| Black race | 80.4 | 68.9 | 70.9 | 0.14 |
| Dry weight body mass index (kg/m2) | 27.6 (7.3) | 29.7 (8.1) | 31.5 (8.9) | 0.004 |
| Obese | 23.9 | 41.8 | 51.8 | <0.001 |
| Current smoker | 21.7 | 24.6 | 22.7 | 0.89 |
| High school or higher education | 63.0 | 65.6 | 61.8 | 0.85 |
| Primary cause of ESRD | 0.47 | |||
| Diabetes | 28.3 | 33.6 | 39.1 | |
| Hypertension | 27.2 | 27.9 | 27.3 | |
| GN | 20.7 | 13.9 | 10.0 | |
| Other | 23.9 | 24.6 | 23.6 | |
| Comorbidities | ||||
| Cardiovascular disease | 40.2 | 43.4 | 52.7 | 0.17 |
| Peripheral vascular disease | 14.1 | 20.5 | 19.9 | 0.49 |
| Rheumatoid arthritis | 7.6 | 15.6 | 15.5 | 0.16 |
| History of cancer | 7.6 | 5.7 | 11.8 | 0.25 |
| Hypertension | 100 | 100 | 100 | >0.99 |
| Chronic pulmonary disease | 27.2 | 27.9 | 32.7 | 0.64 |
| Diabetes | 51.1 | 53.3 | 63.6 | 0.14 |
| Congestive heart failure | 30.4 | 30.3 | 31.8 | 0.97 |
| Cerebrovascular disease | 12.0 | 22.1 | 26.4 | 0.03 |
| Comorbiditya | 39.1 | 40.2 | 48.2 | 0.35 |
| Diagnosed depression | 17.1 | 25.2 | 24.5 | 0.32 |
| Wide Range Achievement Test score | 52.5 (11) | 53.3 (11) | 52.0 (12) | 0.68 |
Data are presented as percentages or means (SD).
a
Comorbidity is ≥4 of the following comorbidities: cardiovascular disease (coronary artery disease, myocardial infarction, angina), congestive heart failure, arthritis, cancer, diabetes, hypertension, or chronic obstructive pulmonary disease.