Table 2.
Distribution of cognitive function scores and cognitive impairment at hemodialysis initiation and 1-year follow-up, by frailty status at hemodialysis initiation
| Frailty Status Measured at Hemodialysis Initiation | 3MS (n=323) | Trail Making Test A (n=320) | Trail Making Test B (n=314) | |||
|---|---|---|---|---|---|---|
| Mean (SD) | % Impairment | Mean (SD) | % Impairment | Mean (SD) | % Impairment | |
| Initiation | ||||||
| Full cohort | 89.8 (7.6) | 10.2 | 55.4 (29) | 7.5 | 161 (83) | 15.0 |
| Nonfrail | 91.1 (7.3) | 6.6 | 48.5 (27) | 4.4 | 143 (80) | 8.7 |
| Intermediately frail | 90.0 (7.6) | 9.8 | 54.7 (25) | 6.7 | 161 (81) | 15.4 |
| Frail | 88.5 (7.6)a | 13.6 | 62.1 (33)a | 11.1 | 176 (84)a | 20.0a |
| 1-yr follow-up | ||||||
| Cohort at follow-up | 88.9 (7.3) | 9.9 | 56.8 (32) | 10.7 | 157 (82) | 16.8 |
| Nonfrail | 90.3 (5.8) | 4.0 | 51.1 (32) | 10.2 | 151 (88) | 12.7 |
| Intermediately frail | 88.9 (8.3) | 11.9 | 57.7 (34) | 12.3 | 151 (83) | 9.3 |
| Frail | 87.7 (7.0)a | 12.7 | 60.7 (28) | 14.8 | 169 (76) | 17.3 |
P values test the difference in mean cognitive function score for those who are intermediately frail and frail compared with those who are nonfrail. 3MS, Modified Mini-Mental State test.
a
P<0.05.