Table 3.
Frailty Status at Hemodialysis Initiation and Cognitive Function at Hemodialysis Initiation and 1-Year Follow-up
| Frailty Status Measured at Hemodialysis Initiation | 3MS | Trail Making Test A | Trail Making Test B |
|---|---|---|---|
| Initiation | |||
| Patients (n) | 323 | 320 | 314 |
| Nonfrail | Reference | Reference | Reference |
| Intermediately frail | −1.29 (−3.05 to 0.48) | 6.12 (−0.94 to 13.18) | 19.87 (−2.34 to 42.08) |
| Frail | −2.37 (−4.21 to −0.53)a | 12.08 (4.73 to 19.43)b | 33.15 (9.88 to 56.42)a |
| P for trend | 0.01 | 0.001 | 0.01 |
| 1-yr follow-up | |||
| Patients (n) | 171 | 168 | 161 |
| Nonfrail | Reference | Reference | Reference |
| Intermediately frail | −1.74 (−4.16 to 0.69) | 6.56 (−4.00 to 17.13) | 1.10 (−28.94 to 31.14) |
| Frail | −2.80 (−5.37 to −0.24)a | 8.48 (−2.62 to 19.58) | 17.42 (−14.29 to 49.14) |
| P for trend | 0.03 | 0.14 | 0.27 |
Data are presented with 95% confidence intervals and are adjusted for sex, age, race, BMI, education, and comorbidity at baseline. 3MS, Modified Mini-Mental State test.
a
P<0.05.
b
P<0.001.