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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: J Immunol. 2015 Nov 13;195(12):5572–5581. doi: 10.4049/jimmunol.1501604

Fig. 4. CD4+ Tregs reduce adoptive transfer keratitis.

Fig. 4

B10.TCRβ/δ−/− recipients females were pre-treated with Tregs from B10 female donors, or with cell diluent only, and received 6 days later an adoptive transfer of CD8+ cells from B10.TCRδ−/− donors. Results from two independent experiments are shown. All mice received 1 × 10^6 CD8+ cells in both experiments, but the Treg treated mice received 0.9 × 10 ^6 Tregs in exp. 1 vs. 0.5 × 10^6 Tregs in exp. 2. Disease incidence is shown as the percent of mice in each group with keratitis each week following adoptive transfer of CD8+ cells. Experiment 1 had 5 recipient mice in the Tregs + CD8 T cells-treated group and 4 recipient mice in the CD8 T cells only-treated group; experiment 2 had 9 recipient mice in each group. Errors bars indicate SEM.