Table 1.
MFN patients | Controls | p-value | |
---|---|---|---|
Demographic data | |||
Number (male, female) | 11 (8, 3) | 10 (6, 4) | ns |
Median age years (range) | 61 (37–83) | 55 (26–67) | ns |
Median disease duration in years (range) | 2 (0.1–4.5) | ||
Questionnaires | |||
Current pain intensity (NRS; 0–10) | 3 (0–7) | 0 | p < 0.05 |
Median NPSI sum score | 0.23 (0.0–0.65) | 0 | p < 0.05 |
Median GCPS sum score (intensity) | 53.3 (37–73) | 0 | p < 0.05 |
Median GCPS sum score (impairment) | 1.5 (0–5) | 0 | p < 0.05 |
Median ADS score | 26 (0–37) | 0 | p < 0.05 |
Median NDS sum score (0–272) | 42 (20–67) | 0 | p < 0.05 |
Median NSS sum score (0–18) | 5 (0–12) | 0 | p < 0.05 |
Electrophysiology | |||
Sural nerve | |||
Sensory nerve action potential (μV) | 4.7 (0–17.1) | 21.2 (9–37.2) | p < 0.05 |
Nerve conduction velocity (m/s) | 41 (0–46.1) | 52.9 (44–56.5) | ns |
ADS, Allgemeine Depressionsskala; GCPS, Graded Chronic Pain Scale; MFN, mixed fiber neuropathy; NDS, Neuropathy Disability Scale; NPSI, Neuropathic Pain Symptom Inventory; ns, not significant; NSS, Neuropathy Symptom Scale; NRS, Numerical Rating Scale.