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Effects of indenoquinoxaline-containing thiazole analogs 4, 6, 8, and 16 as well as acarbose on α-glucosidase activity.
| Ser. | Cpd. No. | α-Glucosidase IC50 (µm) | DF = 100 ± SD |
|---|---|---|---|
| 1 | 4 | 10.19 | 0.21 |
| 2 | 6 | 2.995 | 0.09 |
| 3 | 8 | 0.982 | 0.04 |
| 4 | 16 | 7.029 | 0.13 |
| Standard | Acarbose | 0.316 | 0.02 |
Results represent IC50 (Half maximal inhibitory concentration) of indenoquinoxaline-containing thiazole analogs ± SD as compared to acarbose on α-glucosidase activity.
