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. 2024 Jun 24;39(1):2367128. doi: 10.1080/14756366.2024.2367128

Table 7.

Bioavailability and drug-likeness predictions of substances 4–17 in addition to Acarbose and Gliclazide.

Cpd. No. Lipinski (violations) Veber (violations) Ghose (violations) Egan (violations) Muegge (violations) Bioavailability Score PAINS alerts Synthetic Accessibility
4 0 0 0 0 0 0.55 0 3.44
5 0 0 0 0 0 0.55 0 3.54
6 0 0 0 0 0 0.55 0 3.7
7 0 0 0 0 0 0.55 0 3.43
8 0 0 0 0 0 0.55 0 3.56
9 0 0 0 0 1 0.55 0 3.75
10 0 0 0 0 0 0.55 1 3.66
12 1 0 3 1 3 0.55 1 4.78
13 1 0 3 1 3 0.55 1 4.78
14 0 0 0 0 0 0.55 0 3.03
15 0 0 0 0 0 0.55 0 3.99
16 0 0 0 0 0 0.55 0 4.09
17 0 0 0 0 0 0.55 0 4.09
Acarbose 3 1 4 1 5 0.17 0 7.34
Gliclazide 0 0 0 0 0 0.55 0 3.52