Table 10.

Continuation of toxicity of the most promising hits compared to acarbose and gliclazide.

Cpd. No.	Hepatotoxicity	Skin Sensitisation	T.Pyriformis toxicity (log ug/L)	Minnow toxicity (log mM)
4	Yes	No	0.413	0.321
6	Yes	No	0.287	0.729
8	Yes	No	0.294	0.605
16	Yes	No	0.385	−0.905
Acarbose	No	No	0.285	15.114
Gliclazide	Yes	No	1.038	0.659