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. 2015 Dec 7;5:17457. doi: 10.1038/srep17457

Figure 1. Developmental EE2 exposure affected male sexual behavior of adult F1 mice and their F2 to F4 progenies.

Figure 1

Latencies per second to the first mount (A) and first intromission (B) and frequency of intromissions per minute (C) for each experimental group (Control, EE2 0.1 and EE2 1) (n = 3–5 litters for each group of each generation). Data are expressed as means ± SEM. *p-value < 0.05, **p-value < 0.01 and ***p-value < 0.001; EE2 0.1 or EE2 1 group versus Control group of the same trial test by Bonferroni post-hoc tests after two-way ANOVA. a: p-value < 0.05, aa: p-value < 0.01, aaa: p-value < 0.001, b: p-value = 0.07; significantly different from trial 1 using Friedman tests within each experimental group.