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. 2015 Dec 7;5:17621. doi: 10.1038/srep17621

Figure 8. Depletion of ESRRA suppresses tumorigenicity in vivo.

Figure 8

(A) The Western blot analysis to assess the level of ESRRA following transfection of SCC084 and SCC131 cells with mock and ESRRA siRNA. (B) The effect of mock and ESRRA siRNA on SCC084 and SCC131 cells derived xenografts in nude mice. Top panel: photographs of nude mice showing tumor growth after injection. Bottom panel: excised xenografts. (C) The effect of mock and ESRRA siRNA on the volume of SCC084 and SCC131 cells derived xenografts. (D) The effect of mock and ESRRA siRNA on the weight of SCC084 and SCC131 cells derived xenografts. (E) The Western blot analysis to assess the level of ESRRA in SCC084 and SCC131 cells derived xenografts. N1, N2, N5 and N6 represent xenografts with mock.X1, X2, X5 and X6 represent OSCC cells derived xenografts with ESRRA siRNA. Abbreviations: mock, Stealth RNAiTM mock; and ESRRA siRNA, Stealth RNAiTM ESRRA siRNA. *p < 0.05; **p < 0.01; and ns, non-significant. Four nude mice were used for each transfection.